Research

I believe that all research should be open and freely accessible to everyone. Please contact me if you are interested in a publication, but are unable to get a copy, and I will happily email it to you!

Highlighted

Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression.

John R Shorter, Joëlle A Pasman, Siim Kurvits, Andreas Jangmo, Joonas Naamanka, …, Ole A Andreassen, Martin Tesli, Kelli Lehto, Alfonso Buil, Yi Lu

Nature genetics  ·  13 Nov 2025  ·  pubmed:41233554

All

2026

Pharmacokinetics of Perampanel in Danish Paediatric Patients With Epilepsy Based on Therapeutic Drug Monitoring.

Sara Angelucci, Morten Baltzer Houlind, Maja Stjerne Hansen, Anne Forsingdal Højte Hansen, John R Shorter, Allan Bayat

Basic & clinical pharmacology & toxicology  ·  01 Mar 2026  ·  pubmed:41656002

2025

Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression.

John R Shorter, Joëlle A Pasman, Siim Kurvits, Andreas Jangmo, Joonas Naamanka, …, Ole A Andreassen, Martin Tesli, Kelli Lehto, Alfonso Buil, Yi Lu

Nature genetics  ·  13 Nov 2025  ·  pubmed:41233554

Genome-wide association study of adolescent-onset depression.

Poppy Z Grimes, Brittany L Mitchell, Katherine N Thompson, Qingkun Deng, Xueyi Shen, …, Andrew McIntosh, Mark J Adams, Yi Lu, Heather C Whalley, Alex Sf Kwong

medRxiv : the preprint server for health sciences  ·  26 Sep 2025  ·  pubmed:41040734

Associations of polygenic risk scores for major depression and depression severity: an investigation of 105 623 individuals with 16 years follow-up.

Marit Haram, Andreas Jangmo, Piotr Jaholkowski, Joëlle Pasman, Joeri Meijsen, …, Yi Lu, Thomas Werge, Patrick Sullivan, Ole A Andreassen, Martin Tesli

Molecular psychiatry  ·  17 Sep 2025  ·  pubmed:40962829

2024

Population-Based Risk of Psychiatric Disorders Associated With Recurrent Copy Number Variants

Morteza Vaez, Simone Montalbano, Xabier Calle Sánchez, Kajsa-Lotta Georgii Hellberg, Saeid Rasekhi Dehkordi, …, Jakob Christensen, Liselotte V. Petersen, Marianne Gjørtz Pedersen, Jonas Byberg-Grauholm, Marie Bækvad-Hansen

JAMA Psychiatry  ·  02 Oct 2024  ·  doi:10.1001/jamapsychiatry.2024.1453

The objective of this project was to provide unbiased population-based estimates of prevalence and risk associated with psychiatric disorders for rCNVs and to compare risks across outcomes, rCNV dosage type (deletions or duplications), and locus features.

Quantifying the relative importance of genetics and environment on the comorbidity between mental and cardiometabolic disorders using 17 million Scandinavians

Joeri Meijsen, Kejia Hu, Morten D. Krebs, Georgios Athanasiadis, Sarah Washbrook, …, Nadia Micali, Ole A. Andreassen, Thomas M. Werge, Fang Fang, Alfonso Buil

Nature Communications  ·  13 Jun 2024  ·  doi:10.1038/s41467-024-49507-3

COSGAP: COntainerized Statistical Genetics Analysis Pipelines.

Bayram Cevdet Akdeniz, Oleksandr Frei, Espen Hagen, Tahir Tekin Filiz, Sandeep Karthikeyan, …, Martin Tesli, Yi Lu, Patrick Sullivan, Ole A Andreassen, Eivind Hovig

Bioinformatics advances  ·  09 May 2024  ·  pubmed:38808072

2023

Epidemiological overview of major depressive disorder in Scandinavia using nationwide registers.

Joëlle A Pasman, Joeri J Meijsen, Marit Haram, Kaarina Kowalec, Arvid Harder, …, Ole A Andreassen, Patrick F Sullivan, Alfonso Buil, Martin Tesli, Yi Lu

The Lancet regional health. Europe  ·  28 Mar 2023  ·  pubmed:37265784

2022

THE GENETIC ARCHITECTURE OF MAJOR DEPRESSIVE DISORDER WITH SEVERE OUTCOME IN SCANDINAVIA

Martin Tesli, John Shorter, Andreas Jangmo, Joëlle Pasman, Ole Andreassen, Patrick Sullivan, Thomas Werge, Yi Lu, Alfonso Buil Demur

European Neuropsychopharmacology  ·  01 Oct 2022  ·  doi:10.1016/J.EURONEURO.2022.07.070

80. QUANTIFYING THE ASSORTATIVE MATING OF PSYCHIATRIC DISORDERS AND ITS CONSEQUENCES IN DANISH POPULATION

Saeid Rasekhi Dehkordi, Joeri Meijsen, Dorte Helenius Mikkelsen, Richard Zetterberg, John Shorter, Alfonso Buil, Thomas Werge

European Neuropsychopharmacology  ·  01 Oct 2022  ·  doi:10.1016/J.EURONEURO.2022.07.165

35. A SECOND ITERATION OF THE IPSYCH CROSS-DISORDER STUDY COMPARES ACROSS AND BETWEEN DISORDERS GWAS

Vivek Appadurai, Morten Krebs, Kajsa Lotta Georgii-Hellberg, John Shorter, Joeri Meijsen, iPSYCH Collaborators, Andrew Schork, Thomas Werge

European Neuropsychopharmacology  ·  01 Oct 2022  ·  doi:10.1016/J.EURONEURO.2022.07.124

Infection Polygenic Factors Account for a Small Proportion of the Relationship Between Infections and Mental Disorders

John R. Shorter, Joeri Meijsen, Ron Nudel, Morten Krebs, Jesper Gådin, …, Raquel Nogueira Avelar e Silva, Michael E. Benros, Wesley K. Thompson, Andrés Ingason, Thomas Werge

Biological Psychiatry  ·  01 Aug 2022  ·  doi:10.1016/j.biopsych.2022.01.007

2021

28. ESTIMATING THE GENETIC RELATIONSHIP BETWEEN PSYCHIATRIC DISORDERS AND CARDIOMETABOLIC TRAITS ASSESSED IN A SINGLE NATIONAL COHORT REPRESENTING DENMARK USING MULTIPLE METHODS

Joeri Meijsen, Raquel Nogueira Avelar e Silva, Georgios Athanasiadis, Jesper Gådin, Richard Zetterberg, …, Andrew Schork, Andres Ingason, Thomas Werge, Alfonso Buil, IPSYCH Consortium

European Neuropsychopharmacology  ·  01 Oct 2021  ·  doi:10.1016/J.EURONEURO.2021.07.120

75. A GENOME-WIDE ASSOCIATION STUDY ACROSS PSYCHIATRIC DISORDERS IN THE EXPANDED IPSYCH2015 CASE-COHORT STUDY

John Shorter, Joeri Meijsen, Vivek Appadurai, Anders Rosengren, kajsa Georgii Hellberg, Alfonso Buil, Andrew Schork, Thomas Werge

European Neuropsychopharmacology  ·  01 Oct 2021  ·  doi:10.1016/J.EURONEURO.2021.07.163

2020

Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research

John Sebastian Sigmon, Matthew W Blanchard, Ralph S Baric, Timothy A Bell, Jennifer Brennan, …, Lucy Williams, Mark J Zylka, Martin T Ferris, Leonard McMillan, Fernando Pardo Manuel de Villena

Genetics  ·  01 Dec 2020  ·  doi:10.1534/genetics.120.303596

Collaborative Cross mice reveal extreme epilepsy phenotypes and genetic loci for seizure susceptibility

Bin Gu, John R. Shorter, Lucy H. Williams, Timothy A. Bell, Pablo Hock, …, Yiyun Pan, Darla R. Miller, Ginger D. Shaw, Benjamin D. Philpot, Fernando Pardo‐Manuel de Villena

Epilepsia  ·  27 Aug 2020  ·  doi:10.1111/epi.16617

2019

The Collaborative Cross Graphical Genome

Hang Su, Ziwei Chen, Jaytheert Rao, Maya Najarian, John Shorter, Fernando Pardo Manuel de Villena, Leonard McMillan

openRxiv  ·  29 Nov 2019  ·  doi:10.1101/858142

Whole Genome Sequencing and Progress Toward Full Inbreeding of the Mouse Collaborative Cross Population

John R Shorter, Maya L Najarian, Timothy A Bell, Matthew Blanchard, Martin T Ferris, …, Colton L Linnertz, J Sebastian Sigmon, Darla R Miller, Leonard McMillan, Fernando Pardo-Manuel de Villena

G3 Genes|Genomes|Genetics  ·  01 May 2019  ·  doi:10.1534/g3.119.400039

A Diallel of the Mouse Collaborative Cross Founders Reveals Strong Strain-Specific Maternal Effects on Litter Size

John R Shorter, Paul L Maurizio, Timothy A Bell, Ginger D Shaw, Darla R Miller, Terry J Gooch, Jason S Spence, Leonard McMillan, William Valdar, Fernando Pardo-Manuel de Villena

G3 Genes|Genomes|Genetics  ·  01 May 2019  ·  doi:10.1534/g3.118.200847

2017

Quantitative trait mapping in Diversity Outbred mice identifies two genomic regions associated with heart size

John R. Shorter, Wei Huang, Ju Youn Beak, Kunjie Hua, Daniel M. Gatti, Fernando Pardo-Manuel de Villena, Daniel Pomp, Brian C. Jensen

Mammalian Genome  ·  26 Dec 2017  ·  doi:10.1007/s00335-017-9730-7

Male Infertility Is Responsible for Nearly Half of the Extinction Observed in the Mouse Collaborative Cross

John R Shorter, Fanny Odet, David L Aylor, Wenqi Pan, Chia-Yu Kao, …, Darla R Miller, Elissa J Chesler, Leonard McMillian, Deborah A O’Brien, Fernando Pardo-Manuel de Villena

Genetics  ·  01 Jun 2017  ·  doi:10.1534/genetics.116.199596

Genomes of the Mouse Collaborative Cross

Anuj Srivastava, Andrew P Morgan, Maya L Najarian, Vishal Kumar Sarsani, J Sebastian Sigmon, …, Darla R Miller, Timothy A Bell, Leonard McMillan, Gary A Churchill, Fernando Pardo-Manuel de Villena

Genetics  ·  01 Jun 2017  ·  doi:10.1534/genetics.116.198838

2016

Obp56hModulates Mating Behavior inDrosophila melanogaster

John R Shorter, Lauren M Dembeck, Logan J Everett, Tatiana V Morozova, Gunjan H Arya, Lavanya Turlapati, Genevieve E St. Armour, Coby Schal, Trudy F C Mackay, Robert R H Anholt

G3 Genes|Genomes|Genetics  ·  01 Oct 2016  ·  doi:10.1534/g3.116.034595

2015

The Effects of Royal Jelly on Fitness Traits and Gene Expression in Drosophila melanogaster

John R. Shorter, Matthew Geisz, Ergi Özsoy, Michael M. Magwire, Mary Anna Carbone, Trudy F. C. Mackay

PLOS ONE  ·  30 Jul 2015  ·  doi:10.1371/journal.pone.0134612

Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior

John Shorter, Charlene Couch, Wen Huang, Mary Anna Carbone, Jason Peiffer, Robert R. H. Anholt, Trudy F. C. Mackay

Proceedings of the National Academy of Sciences  ·  22 Jun 2015  ·  doi:10.1073/pnas.1510104112

2012

A Genetic Analysis of the Stinging and Guarding Behaviors of the Honey Bee

John R. Shorter, Miguel Arechavaleta-Velasco, Carlos Robles-Rios, Greg J. Hunt

Behavior Genetics  ·  11 Feb 2012  ·  doi:10.1007/s10519-012-9530-5

2011

A review on self-destructive defense behaviors in social insects

J. R. Shorter, O. Rueppell

Insectes Sociaux  ·  04 Dec 2011  ·  doi:10.1007/s00040-011-0210-x

2009

How do fighting ability and nest value influence usurpation contests in Polistes wasps?

Elizabeth A. Tibbetts, John R. Shorter

Behavioral Ecology and Sociobiology  ·  25 Apr 2009  ·  doi:10.1007/s00265-009-0764-z

2008

The effect of juvenile hormone on temporal polyethism in the paper wasp Polistes dominulus

J. R. Shorter, E. A. Tibbetts

Insectes Sociaux  ·  15 Sep 2008  ·  doi:10.1007/s00040-008-1026-1